NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in all living cells that plays a critical role in numerous biological processes essential for life and health. It is a molecule that assists enzymes in driving chemical reactions in the body, particularly those involved in energy production and cellular repair.

NAD+ is essential in the Krebs Cycle, which turns food molecules into energy. It enables DNA repair and cellular regeneration. NAD+ also works with the neuro-transmission of signals between neurons (including in the brain).

Lower levels of NAD+ result in your cells not being able to metabolise as much of the food molecules as may be needed, making less energy available for you to use. As cells replicate, DNA is damaged and, without repairing this damage, copies of this damage can be passed on to future replications of the cells. Without the NAD+ supporting neurotransmission between cells, so the signal generated by one neuron is not passed on as efficiently as possible to the next, leading to a weaker, slower signal. These slow signals add up to cogitative slowing and even cogitative decline.

NAD+ is taken to support energy production, repair damaged cells and promote healthy aging. Here’s how it can be taken:

1. Sub-cutaneous injection (sub.cut.): The VAION+ PEN is the first sub.cut. auto-injector pen for NAD+. It precisely administers the right amount of NAD+ 4mm under the fatty layers of the skin in the stomach, delivering it efficiently into the blood stream. It is the most effective way to maintain NAD+ levels in the body because of it’s high absorption and quick effects which is ideal for those seeking immediate results or with specific health needs. The dose is small and administered every other day to build up and maintain your healthy NAD+ levels.
2. Intramuscular Injection (IM): An effective way to maintain NAD+ levels in the body is to have small IM injections of NAD+ multiple times a month, which tops-up the system very effectively.
3. Intravenous (IV): The fastest way to boost your NAD+ levels is through IV drip, where 500mg/1000mg of NAD+ can be administered in a matter of 3 hours +. The downside of this is that the experience can be unpleasant, with strong tightening of the chest, waves of nausea and abdominal pain. The huge boost to the system is an excellent way to get to optimal NAD+ levels immediately, but wears off over time unless administered again or supplemented in another way, such as IM or Sub.cut injections.
4. Orally: NAD+ can be swallowed in pill form, but the bioavailability (the amount your body can absorb) is extremely low as NAD+ is a fragile molecule and is broken down during digestion. NAD+ precursor molecules can also be consumed and are more stable through digestion but there are questions over the safety of such supplements. The FDA is currently investigating these precursors as there may be side effects, such as cancer, caused by heavy consumption of these supplements.

Using the VAION+ PEN, you should build up your NAD+ levels over the first three days of use by taking a dose on day 1, 2 and 3. After the first three days, you should use your VAION+ PEN every other day. We recommend taking the NAD+ in the morning so you can enjoy the benefits of your top up throughout the day.

Unless otherwise advised by a qualified medic/healthcare provider, you should take 0.3ml (50mg) of NAD+ per injection. For three days, take it every day, then every other day thereafter.

Your experience will be unique to you and depends on many factors, especially your current NAD+ levels, age, alcohol consumption and more. Many customers experience the following:

1. Day 1: 15-30 minutes after the first injection, some customers report a substantial boost in “nervous energy” which has been described both as “waking up like a bucket of cold water to the face” and also “like having 1/2 a cup of coffee too much”. You may feel a tingling sensation for a few minutes in your fingertips and you may also feel warm. These feelings will subside and are totally normal.
2. Days 2, 3 and 5: As your body adjusts to the boost in NAD+, so the feelings you experienced on day 1 are likely to decrease with each dose. You will continue to feel the elevated focus and energy, but it will be less “nervous energy” and more productive energy. You should see athletic performance enhancements as well as recovery speeds from exercise improve. You may also experience a decreased strength of cravings for certain food types, alcohol and nicotine.
3. Days 7-30: Each injection will bring your NAD+ levels up until, over time, your body reaches its natural optimum level. At this point, the NAD+ injections are simply topping up and the difference between before and after the injection will be less pronounced. You should feel an enduring energy and focus compared to before you started using your NAD+ pen and your exercise and recovery rates should remain elevated.

The VAION+ PEN is the easiest, most painless and most convenient way to top up your NAD+ levels.

Click here for video Instructions on how to use your VAION+ Pen.

1. Remove the pen and a cartridge from the packaging and allow the NAD+ to rest at room temperature for 2-3 minutes.
2. PULL the lid of the pen so it comes off, exposing the clear cartridge holder.
3. UNSCREW the clear cartridge holder from the base.
4. Press the plunger (if exposed) into the base of the pen with a finger.
5. Take the cartridge and insert into the clear cartridge holder with the silver tip going in first.
6. SCREW the clear cartridge holder with the NAD+ cartridge inside it onto the base FIRMLY.
7. Twist the base of the pen until the dose meter is all the way out.
8. Push the dose meter and watch the plunger move up inside the cartridge holder. Repeat this until the plunger is touching the bung in the bottom of the cartridge and you feel resistance.
9. Continue with “daily use of the pen”, below.

Please note that it is unusual but entirely NORMAL to:

• experience a drop of NAD+ on the skin after the injection
• have a tiny drop of blood on the skin after the injection
• experience a small bruise at the site of the injection (this is due to the needle not being kept still during the injection)
• have a red mark around the site of the injection for a short while after the injection. It will disappear after a little while and is causing you no harm, being well within the accepted guidelines for pH of injectables. If you are worried about the appearance of the mark, consider injecting in area that is covered by clothing, such as the buttock.

Click here for video Instructions on how to use your VAION+ Pen.

1. Take a 4mm needle tip from the pack and gently but firmly screw it on to the end of the pen. Do not remove the needle tip cover yet.
2. Clean the injection site with an alcohol wipe provided in the pack. It is good to select a fatty area, such as the belly, buttock or thigh.
3. Remove the needle tip covers (there is an inner and an outer one)
4. Without putting the pen down, twist the base until the pointer lines up with your dose, usually 30 units, which is 0.3ml.
5. Gently pinch the skin around the injection site to pull it away from the muscle a little (it only needs to be 4mm away so don’t pull hard!)
6. Place the pen on the injection site and press the pen down to get through the skin. Try hard to keep the pen steady to prevent bruising.
7. Press the button at the base of the pen (which will now be the furthest point of the pen from your skin). This will depress the plunger and administer the NAD+.
8. Once the dose is all administered, count down three seconds and then remove the needle.
9. Replace the outer needle tip cover carefully and unscrew the needle tip with the cover on it.
10. Replace the VAION+ pen cap and stow the pen back in the fridge.
11. Dispose of the needle tip in the sharps bin provided.
12. Make sure to rotate the site of the injection, as repeated injections in the same site can cause damage and “dimpling” of the skin.

Please note that it is unusual but entirely NORMAL to:

• experience a drop of NAD+ on the skin after the injection
• have a tiny drop of blood on the skin after the injection
• experience a small bruise at the site of the injection (this is due to the needle not being kept still during the injection)
• have a red mark around the site of the injection for a short while after the injection. It will disappear after a little while and is causing you no harm, being well within the accepted guidelines for pH of injectables. If you are worried about the appearance of the mark, consider injecting in area that is covered by clothing, such as the buttock.

The VAION+ PEN should be stored, with its active cartridge of NAD+, between 2 and 8 degrees Celsius (35.6-46.4 Fahrenheit). A domestic fridge is a great place. If you are travelling, it is highly recommended to use an insulated case with ice gel packs.

NAD+ cartridges that are not yet being used should also be stored in the fridge.

NAD+ remains effective for up to 18 months if kept properly chilled.

Yes.

Your cartridges can contain 3ml when filled to the top, but doing so makes it much more likely for the bung to come out in transit.

As a result, we send you two cartridges with just over 1.5ml in each. We slightly over-fill each cartridge so you get every dose you need throughout the month, despite losing a few drops along the way (clearing any bubbles, discarded with the needle, human error etc).

Special packaging with cooling is used to ensure NAD+ is delivered in optimal condition.